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Mixtral 8x22B Instruct vs Qwen 2.5 72B

How do these models stack up? Below is an expert side-by-side comparison of specifications, context window capacity, live pricing per million tokens, and standardized benchmark scores for Mixtral 8x22B Instruct and Qwen 2.5 72B.

Mistral

Mixtral 8x22B Instruct

Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b). It uses 39B active parameters out of 141B, offering unparalleled cost efficiency for its size. Its strengths include: - strong math, coding,...

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Alibaba

Qwen 2.5 72B

Qwen 2.5 72B is Alibaba Cloud's flagship open-weight large language model from the Qwen 2.5 generation, delivering GPT-4-class performance across general reasoning, coding, mathematics, and multilingual tasks with strong Chinese-language superiority. It supports a 131,072-token context window and is available under a permissive Apache 2.0 license for both research and commercial use, making it one of the most popular open-weight alternatives to Llama for bilingual applications.

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Technical Specifications

SpecificationMixtral 8x22B InstructQwen 2.5 72B
ProviderMistralAlibaba
Context Window65,536 tokens131,072 tokens
Agent SuitabilityN/A88/100
Time to First Token (TTFT)N/A280 ms
Deployment Modelself hostableself hostable
Production Stabilitystablestable
API AvailableYesYes
Released Date2024-04-172025-09-19

API Pricing Comparison

Input Price per Million Tokens

Mixtral 8x22B Instruct

$2.00

Qwen 2.5 72B

$0.40

Output Price per Million Tokens

Mixtral 8x22B Instruct

$6.00

Qwen 2.5 72B

$0.80

Want to test both models live?

Run side-by-side prompt prompts in our dynamic Sandbox. Check execution speeds, latency metrics, and compute actual costs in real-time.

Benchmark Performance Metrics

Scores show the raw performance percentages verified across key evaluation suites. Higher bars indicate superior accuracy and capability in that domain.

Mixtral 8x22B Instruct Quirks & Gotchas

No developer gotchas reported.

Qwen 2.5 72B Quirks & Gotchas

  • โ–ธStrong bilingual (ZH/EN) performance โ€” best open model for Chinese-language tasks
  • โ–ธSelf-hostable via vLLM or Ollama with 4-bit quantization