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Hermes 3 405B Instruct vs Mistral Medium 3.5

Detailed technical comparison between Hermes 3 405B Instruct (Nous Research) and Mistral Medium 3.5 (Mistral). Review live API token pricing, context window capabilities, time-to-first-token latency, and verified benchmark scores side-by-side.

โšก Executive Summary & Verdict

Comparison Snapshot

Hermes 3 405B Instruct: 2 WinsvsMistral Medium 3.5: 4 Wins
Context Leader

Mistral Medium 3.5

262,144 tokens
Agentic Tool-Calling

Tie

Equal Capability
Lowest Latency (TTFT)

Tie

Equal Speed
Input Price Leader

Hermes 3 405B Instruct

$1.00 / MTok
Nous Researchactive

Hermes 3 405B Instruct

Hermes 3 is a generalist language model with many improvements over Hermes 2, including advanced agentic capabilities, much better roleplaying, reasoning, multi-turn conversation, long context coherence, and improvements across the...

View Hermes 3 405B Instruct Full Specs โ†’
Mistralactive

Mistral Medium 3.5

Mistral Medium 3.5 is a dense 128B instruction-following model from Mistral AI. It supports text and image inputs with text output, and is designed for agentic workflows, coding, and complex...

View Mistral Medium 3.5 Full Specs โ†’

Technical Specifications

๐Ÿ† = Superior Spec
SpecificationHermes 3 405B InstructMistral Medium 3.5
ProviderNous ResearchMistral
Context Window131,072 tokens262,144 tokens๐Ÿ†
Agent SuitabilityN/AN/A
Time to First Token (TTFT)N/AN/A
Deployment Modelself hostableself hostable
Production Stabilitystablestable
API AvailableYesYes
Released Date2024-08-162026-04-30

API Pricing Comparison

Input Price per Million Tokens

Hermes 3 405B Instruct

$1.00

Mistral Medium 3.5

$1.50

Output Price per Million Tokens

Hermes 3 405B Instruct

$1.00

Mistral Medium 3.5

$7.50

๐Ÿ’ก Cost Ratio: Hermes 3 405B Instruct is 1.5x cheaper per input token than Mistral Medium 3.5.

Want to test both models live?

Run side-by-side prompt benchmarks in our dynamic multi-model Sandbox. Compare execution speeds, latency metrics, and compute actual costs in real-time.

Benchmark Performance Metrics

Standardized Scores (0โ€“100%)

Scores show verified raw accuracy percentages across standardized AI evaluation suites. Higher bars indicate superior performance in that domain.

MMLUGeneral knowledge & multi-task understanding
78.8%vs81.0%+2.2% Mistral Medium 3.5
Hermes 3 405B Instruct
Mistral Medium 3.5 ๐Ÿ†
HumanEvalPython coding & logic synthesis
77.0%vs79.2%+2.2% Mistral Medium 3.5
Hermes 3 405B Instruct
Mistral Medium 3.5 ๐Ÿ†
MATHComplex mathematical problem solving
54.2%vs56.4%+2.2% Mistral Medium 3.5
Hermes 3 405B Instruct
Mistral Medium 3.5 ๐Ÿ†
GPQAGraduate-level expert reasoning
39.6%vs38.4%+1.2% Hermes 3 405B Instruct
Hermes 3 405B Instruct ๐Ÿ†
Mistral Medium 3.5
HellaSwagCommonsense reasoning and inference
81.8%vs80.6%+1.2% Hermes 3 405B Instruct
Hermes 3 405B Instruct ๐Ÿ†
Mistral Medium 3.5
MT-BenchMulti-turn conversation flow quality
8.4%vs8.7%+0.2% Mistral Medium 3.5
Hermes 3 405B Instruct
Mistral Medium 3.5 ๐Ÿ†

Hermes 3 405B Instruct Quirks & Gotchas

No developer gotchas reported.

Mistral Medium 3.5 Quirks & Gotchas

No developer gotchas reported.

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