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Claude Sonnet 4.5 vs Mixtral 8x22B Instruct

How do these models stack up? Below is an expert side-by-side comparison of specifications, context window capacity, live pricing per million tokens, and standardized benchmark scores for Claude Sonnet 4.5 and Mixtral 8x22B Instruct.

Anthropic

Claude Sonnet 4.5

Claude Sonnet 4.5 is Anthropic’s most advanced Sonnet model to date, optimized for real-world agents and coding workflows. It delivers state-of-the-art performance on coding benchmarks such as SWE-bench Verified, with...

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Mistral

Mixtral 8x22B Instruct

Mistral's official instruct fine-tuned version of [Mixtral 8x22B](/models/mistralai/mixtral-8x22b). It uses 39B active parameters out of 141B, offering unparalleled cost efficiency for its size. Its strengths include: - strong math, coding,...

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Technical Specifications

SpecificationClaude Sonnet 4.5Mixtral 8x22B Instruct
ProviderAnthropicMistral
Context Window1,000,000 tokens65,536 tokens
Agent Suitability91/100N/A
Time to First Token (TTFT)380 msN/A
Deployment Modelmanaged apiself hostable
Production Stabilitystablestable
API AvailableYesYes
Released Date2025-09-292024-04-17

API Pricing Comparison

Input Price per Million Tokens

Claude Sonnet 4.5

$3.00

Mixtral 8x22B Instruct

$2.00

Output Price per Million Tokens

Claude Sonnet 4.5

$15.00

Mixtral 8x22B Instruct

$6.00

Want to test both models live?

Run side-by-side prompt prompts in our dynamic Sandbox. Check execution speeds, latency metrics, and compute actual costs in real-time.

Benchmark Performance Metrics

Scores show the raw performance percentages verified across key evaluation suites. Higher bars indicate superior accuracy and capability in that domain.

MMLUGeneral knowledge & multi-task understanding
8950.0%vsN/A
Claude Sonnet 4.5
Mixtral 8x22B Instruct
HumanEvalPython coding & logic synthesis
9280.0%vsN/A
Claude Sonnet 4.5
Mixtral 8x22B Instruct
MATHComplex mathematical problem solving
8000.0%vsN/A
Claude Sonnet 4.5
Mixtral 8x22B Instruct
GPQAGraduate-level expert reasoning
6250.0%vsN/A
Claude Sonnet 4.5
Mixtral 8x22B Instruct
HellaSwagCommonsense reasoning and inference
9580.0%vsN/A
Claude Sonnet 4.5
Mixtral 8x22B Instruct
MT-BenchMulti-turn conversation flow quality
930.0%vsN/A
Claude Sonnet 4.5
Mixtral 8x22B Instruct

Claude Sonnet 4.5 Quirks & Gotchas

  • Excellent for long-form writing and nuanced document analysis
  • Slightly slower than Sonnet 4.6 — upgrade for production agentic use

Mixtral 8x22B Instruct Quirks & Gotchas

No developer gotchas reported.