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Claude Opus 4 vs Qwen 2.5 72B

How do these models stack up? Below is an expert side-by-side comparison of specifications, context window capacity, live pricing per million tokens, and standardized benchmark scores for Claude Opus 4 and Qwen 2.5 72B.

Anthropic

Claude Opus 4

Claude Opus 4 is benchmarked as the world’s best coding model, at time of release, bringing sustained performance on complex, long-running tasks and agent workflows. It sets new benchmarks in...

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Alibaba

Qwen 2.5 72B

Qwen 2.5 72B is Alibaba Cloud's flagship open-weight large language model from the Qwen 2.5 generation, delivering GPT-4-class performance across general reasoning, coding, mathematics, and multilingual tasks with strong Chinese-language superiority. It supports a 131,072-token context window and is available under a permissive Apache 2.0 license for both research and commercial use, making it one of the most popular open-weight alternatives to Llama for bilingual applications.

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Technical Specifications

SpecificationClaude Opus 4Qwen 2.5 72B
ProviderAnthropicAlibaba
Context Window200,000 tokens131,072 tokens
Agent SuitabilityN/A88/100
Time to First Token (TTFT)N/A280 ms
Deployment Modelmanaged apiself hostable
Production Stabilitystablestable
API AvailableYesYes
Released Date2025-05-222025-09-19

API Pricing Comparison

Input Price per Million Tokens

Claude Opus 4

$15.00

Qwen 2.5 72B

$0.40

Output Price per Million Tokens

Claude Opus 4

$75.00

Qwen 2.5 72B

$0.80

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Benchmark Performance Metrics

Scores show the raw performance percentages verified across key evaluation suites. Higher bars indicate superior accuracy and capability in that domain.

MMLUGeneral knowledge & multi-task understanding
9050.0%vsN/A
Claude Opus 4
Qwen 2.5 72B
HumanEvalPython coding & logic synthesis
9300.0%vsN/A
Claude Opus 4
Qwen 2.5 72B
MATHComplex mathematical problem solving
8540.0%vsN/A
Claude Opus 4
Qwen 2.5 72B
GPQAGraduate-level expert reasoning
7230.0%vsN/A
Claude Opus 4
Qwen 2.5 72B
HellaSwagCommonsense reasoning and inference
9650.0%vsN/A
Claude Opus 4
Qwen 2.5 72B
MT-BenchMulti-turn conversation flow quality
945.0%vsN/A
Claude Opus 4
Qwen 2.5 72B

Claude Opus 4 Quirks & Gotchas

No developer gotchas reported.

Qwen 2.5 72B Quirks & Gotchas

  • Strong bilingual (ZH/EN) performance — best open model for Chinese-language tasks
  • Self-hostable via vLLM or Ollama with 4-bit quantization